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, JOC ǥ 2018-12-07




: Hydrogen-Bonding-Assisted Imine Formation
: The ketimine formation with benzophenone has been a challenge. The cover image shows a newly developed recipe for the direct formation of ketimines with benzophenone derivatives. The key idea is to utilize inter- and intramolecular hydrogen bonds mediated by the 2-hydroxyphenyl groups shown in the sketch of the transition state. This work is mainly done by Dr. Min-Seob Seo and Ms. Sumin Jang from the Prof. Hyunwoo Kim's research group.