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ӹ񱳼, ChemComm Front Cover 2019-05-22

: Tunable regulatory activities of 1,10-phenanthroline derivatives towards acid sphingomyelinase and Zn(II)–amyloid-


The cover image shows 1,10-phenanthroline derivatives as chemical modulators for acid sphingomyelinase, Zn(II)-bound amyloid-, or both. Utilizing such chemical modulators, both the aggregation and clearance of A could be controlled. This work was mainly carried out by two graduate students, Yelim Yi and Jiyeon Han, from Professor Mi Hee Lims group.