1976: B.S. Seoul National University
1978: M.S. Seoul National University
1984: Ph.D. Brandeis University
Professional Experiences
1984-1986: Post-Doc, MIT
1986-1988: Assistant Professor, KAIST
1988-1995: Associate Professor, KAIST
1995-2019.3: Professor, KAIST
Brief Introduction
Research topics
- DNA Repair, Recombination and Replication
- Novel Drug Development against Pandemic Influenza Virus
- Structural Biology and Chemical Biology
Representative publications
1. "Structural Characterization Reveals That a PilZ Domain Protein Undergoes Substantial Conformational Change upon Binding to c-di-GMP", Protein Science 2011, 20(2), 270-277.
2. "Structure and Function of the Regulatory HRDC Domain from Human Bloom Syndrome Protein", Nucleic Acids Res. 2010, 38(21), 7764-7777.
3. "Structure of PP4397 Reveals the Molecular basis for Different c-di-GMP Binding Modes by PilZ Domain Proteins", J.Mol.Biol. 2010, 398(1), 97-110.
4. "NMR Spectroscopic Elucidation of the B-Z Transition of a DNA Double Helix Induced by the ZαDomain of Human ADAR1", J. Am. Chem. Soc. 2009, 131(32), 11485-11491.
5. "Structural and Dynamics Study of DNA Dodecamer Duplexes That Contain Un-, Hemi-, or Fully- Methylated GATC Sites", J. Am. Chem. Soc. 2008, 130(52), 17688-17696.
