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  • Lee, Jie-Oh   Professor
  • Biochemistry (2001 ~ 2019.3)
  • Ph. D. 1995 Harvard University
  • WEBPAGE : http://
  • E-MAIL : @
  • Tel/Office : -- (Office), (Lab) / (Room)

Education

1987: B.S. Seoul National University
1989: M.S. Seoul National University
1995: Ph.D. Harvard University

Professional Experiences

1996-2000: Postdoctoral fellow, Memorial Sloan Kettering Cancer Center
2000-2001: Assistant professor, University of Maryland at Baltimore County
2001-2019.3: Professor, KAIST

Brief Introduction

Research topics

- X-ray Crystallography
- Artificial LRR Protein Design
- Drug Design

Representative publications

1. "Structural Biology of Toll-like Receptor Family.", Ann. Rev. Biochem. 2011, 80, 917.
2. "Recognition of Lipopeptide Patterns by Toll-like Receptor 2- oll-like Receptor 6 Heterodimer.", Immunity. 2009, 31, 873.
3. "The Structural basis of Lipopolysaccharide Recognition by the TLR4-MD-2 Complex.", Nature. 2009, 458, 1191.
4. "Structures of the Toll-like Receptor Family and Its Ligand Complexes.", Immunity. 2008, 29, 182.
5. "Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide.", Cell. 2007, 130, 1071.
6. "Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran.", Cell. 2007, 130, 906.